반응 #88073

ord-160d257143854337814bdb442468d826

반응 방정식

CC(C)(C)OC(=O)N1CCC(=O)CC1
N-Boc-piperid-4-one
NCCc1ccc(Cl)cc1
2-(4-chlorophenyl)ethylamine
COC(=O)c1ccc(C=O)cc1
methyl 4-formylbenzoate
→
COC(=O)c1ccc(CN(CCc2ccc(Cl)cc2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1
title compound
COC(=O)c1ccc(CN(CCc2ccc(Cl)cc2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1
tert-Butyl 4-((4-chlorophenethyl)(4-(methoxycarbonyl)benzyl)amino)piperidine-1-carboxylate

반응물

CC(C)(C)OC(=O)N1CCC(=O)CC1
N-Boc-piperid-4-one
NCCc1ccc(Cl)cc1
2-(4-chlorophenyl)ethylamine
COC(=O)c1ccc(C=O)cc1
methyl 4-formylbenzoate

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared according to Procedure 1B starting from N-Boc-piperid-4-one, 2-(4-chlorophenyl)ethylamine, and methyl 4-formylbenzoate.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09440953B2uspto-grants-2016_09