반응 #87647

반응 방정식

2-chloro-4-methoxybenzoic acid

2,2,2-trifluoro-N-(hydroxymethyl)acetamide

H2SO4

→

desired product

수율 39.9%

5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid

수율 39.9%

반응 조건

후처리

1. 1
   기타The title compound was prepared

실험 절차

The title compound was prepared according to the procedure described in step-1 of Intermediate-26 by using 2-chloro-4-methoxybenzoic acid (0.060 g), 2,2,2-trifluoro-N-(hydroxymethyl)acetamide (0.050 g) and H2SO4 (2 mL) to afford 0.040 g of the desired product.

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