반응 #8759

반응 방정식

3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

potassium carbonate

thiophen-3-yl-methylamine

acetonitrile

→

title compound

[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-thiophen-3-yl-methylamine

용매

water

반응 조건

후처리

1. 1
   workup.ADDITIONis added to the reaction mixture
2. 2
   온도before heating

실험 절차

The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, thiophen-3-yl-methylamine (prepared according to Synthetic Metals, 26 (1988)153–168) and acetonitrile essentially as described above in example 18, except that water (0.40 mL) is added to the reaction mixture before heating. Purity by LC/MS (APCI)=100%, [M+H]+=357.

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