반응 #8755

반응 방정식

3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

potassium carbonate

4-chlorobenzylamine

→

title compound

(4-chloro-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

용매

acetonitrile

반응 조건

후처리

1. 1
   세척is eluted

실험 절차

The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, 4-chlorobenzylamine and acetonitrile essentially as described above in example 18 except that the column is eluted using a gradient of 40% ethyl acetate in heptane, to 100% ethyl acetate. Purity by LC/MS (APCI)=100%, [M+H]+=385.

출처