반응 #87294

반응 방정식

4-(1-Oxoindan-2-ylidenemethyl)benzonitrile

N-bromosuccinimide

benzoyl peroxide

→

15a

4-(1-Bromo-3-oxoindan-2-ylidenemethyl)benzonitrile

용매

carbon tetrachloride

반응 조건

후처리

1. 1
   기타Reaction mixture
2. 2
   온도was reflux for 9 h
3. 3
   온도cooled down
4. 4
   여과precipitate was filtered off
5. 5
   세척washed with diethyl ether (10×30 mL) for removal of N-hydroxysuccinimide Precipitate
6. 6
   기타was dried under vacuum

실험 절차

4-(1-Oxoindan-2-ylidenemethyl)benzonitrile (2.18 g, 8.9 mmol) was dissolved in carbon tetrachloride (40 mL). N-bromosuccinimide (1.58 g, 8.9 mmol) and benzoyl peroxide (100 mg) were added in one portion. Reaction mixture was reflux for 9 h, cooled down; precipitate was filtered off and washed with diethyl ether (10×30 mL) for removal of N-hydroxysuccinimide Precipitate was dried under vacuum, provided pure 15a.

출처