반응 #87290

반응 방정식

triethylenetetramine

oleoyl chloride

→

hydrogen chloride

triethylenetetramine HCl

용매

dichloromethane

dichloromethane

반응 조건

후처리

1. 1
   workup.DISSOLUTIONdissolved
2. 2
   기타to react at 5° C. for 3 hours

실험 절차

1.12 g (7.5 mmol) of triethylenetetramine was added to 25 mL of dichloromethane and dissolved with stirring in an ice water bath at 5° C. for 30 minutes. To the solution, a solution of 2.00 g (6.0 mmol) of oleoyl chloride in 20 mL of dichloromethane in a separate reactor was added slowly dropwise while it was allowed to react at 5° C. for 3 hours. Due to hydrogen chloride produced during the reaction, unreacted triethylenetetramine HCl was precipitated. Before the end of the reaction, the upper layer solution was taken and analyzed by thin layer chromatography (TLC) with a mobile phase of ethanol:chloroform (2:1) to determine whether the reaction was completed.

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