반응 #8716

반응 방정식

2-hydroxylbenzonitrile

potassium carbonate

ethyl bromide

→

colorless liquid

수율 97.1%

2-Ethoxy-benzonitrile

수율 97.1%

용매

acetone

반응 조건

후처리

1. 1
   온도under reflux overnight
2. 2
   여과The solid is filtered off
3. 3
   기타the solvent is removed in vacuo
4. 4
   workup.DISTILLATIONthe residue is distilled in vacuo

실험 절차

25 g (210 mmol) of 2-hydroxylbenzonitrile are heated, together with 87 g of potassium carbonate and 34.3 g (314.8 mmol) of ethyl bromide, in 500 ml of acetone under reflux overnight. The solid is filtered off, the solvent is removed in vacuo and the residue is distilled in vacuo. 30.0 g (97%) of a colorless liquid are obtained.

출처