반응 #86609

반응 방정식

N2-(tert-butoxycarbonyl)-N,N2-dimethyl-N-[3-(triphenylphosphonio)propyl]glycinamide bromide

trifluoroacetic acid

→

title compound

N,N2-dimethyl-N-[3-(triphenylphosphonio)propyl]-glycinamide trifluoroacetate

반응 조건

후처리

1. 1
   기타the volatiles were removed under high vacuum
2. 2
   세척washed with aqueous NaHCO3
3. 3
   세척The organic layer was then washed with water
4. 4
   농축concentrated

실험 절차

N2-(tert-butoxycarbonyl)-N,N2-dimethyl-N-[3-(triphenylphosphonio)propyl]glycinamide bromide (280 mg, 0.48 mmol) was dissolved in trifluoroacetic acid (1.9 mL, 25 mol) at room temperature. After 30 minutes, the volatiles were removed under high vacuum and the crude product taken up in methylene chloride and washed with aqueous NaHCO3. The organic layer was then washed with water and concentrated to give the title compound in quantitative yield.

출처