반응 #86307

반응 방정식

N-benzoyl-D,L-isoleucyl-L-proline benzyl ester

hydrogen

→

N-benzoyl-D,L-isoleucyl-L-proline

용매

methanol

반응 조건

후처리

1. 1
   기타to react at room temperature for 3 h
2. 2
   여과filtered
3. 3
   농축concentrated under reduced pressure
4. 4
   기타to remove the solvent
5. 5
   기타to give a colourless sticky matter (1.04 g, 99%), which
6. 6
   기타was directly used for the next reaction

실험 절차

N-benzoyl-D,L-isoleucyl-L-proline benzyl ester (1.1 g) was dissolved in methanol (15 ml), and 10% palladium-carbon (120 mg) was added. The resulting mixture aerated with hydrogen was allowed to react at room temperature for 3 h, filtered and concentrated under reduced pressure to remove the solvent to give a colourless sticky matter (1.04 g, 99%), which was directly used for the next reaction.

출처