반응 #85835

반응 방정식

tert-butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate

→

tert-butyl 4-(4-amino-2-fluorophenyl)piperazine-1-carboxylate

용매

MeOH

반응 조건

후처리

1. 1
   여과The reaction was filtered
2. 2
   농축concentrated
3. 3
   기타to give gray yellow oil

실험 절차

To a solution of tert-butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate (5 mmol) in MeOH (30 mL) was added Pd/C (1 g), then the mixture was stirred for 18 hours at 20° C. under 1 atm. H2. The reaction was filtered and concentrated to give gray yellow oil. MS (m/z): 296 (M+H)+

출처