반응 #85530

반응 방정식

2-(5-amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonyl chloride

4-chlorobenzylamine

NMM

→

title compound

수율 16.1%

2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid 4-chlorobenzylamide

수율 16.1%

용매

methanol

반응 조건

실험 절차

the title compound (21 mg) was prepared from crude 2-(5-amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonyl chloride (100 mg, 0.30 mmol), 4-chlorobenzylamine (74 μL, 0.60 mmol) and PS-NMM (0.320 g, 0.60 mmol) in 5 mL of methanol. MS (m/z, ES+): 434.4 (Cl35 M+1, 100%), 436.4 (Cl37 M+1, 40%). Yield=16%.

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