반응 #85467

ord-b22517412c8d409da5bfd66214415b4d

반응 방정식

CCOc1ccccc1I
ethoxyiodobenzene
O=C1Nc2cc(F)c(Cl)cc2C1=O
5-chloro-6-fluoroisatin
O=C1Nc2ccccc2C1=O
isatin
CCOc1ccccc1C1(O)C(=O)Nc2cc(F)c(Cl)cc21
title compound
CCOc1ccccc1C1(O)C(=O)Nc2cc(F)c(Cl)cc21
5-Chloro-3-(2-ethoxyphenyl)-6-fluoro-3-hydroxy-1,3-dihydroindol-2-one

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared in analogy to example a.1 using 5-chloro-6-fluoroisatin as isatin II and ethoxyiodobenzene (to form the Grignard reagent).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09434713B2uspto-grants-2016_09