반응 #85126

반응 방정식

ethyl 2-{4-[5-Chloro-2-(difluormethoxy)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}butanoate

lithium hydroxide

→

2-{4-[5-Chloro-2-(difluoromethoxy)phenyl]-5-methoxy-2-oxopyridine-1(2H)-yl}butanoic acid

반응 조건

실험 절차

415 mg (0.97 mmol) of ethyl 2-{4-[5-Chloro-2-(difluormethoxy)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}butanoate (racemate) were hydrolysed with lithium hydroxide according to General Method 6B. Yield: 348 mg (93% of theory)

출처