반응 #85123

반응 방정식

4-[5-chloro-2-(difluoromethoxy)phenyl]-5-methoxypyridin-2(1H)-one

2-bromopropanoic acid

→

2-{4-[5-Chloro-2-(difluoromethoxy)phenyl]-5-methoxy-2-oxopyridin-1(2H)-yl}propanoic acid

반응 조건

후처리

1. 1
   기타according to General Method 4A at 90° C

실험 절차

127 mg (0.42 mmol) of 4-[5-chloro-2-(difluoromethoxy)phenyl]-5-methoxypyridin-2(1H)-one and 1.5 eq. of 2-bromopropanoic acid (racemate) were reacted according to General Method 4A at 90° C. Yield: 220 mg of crude product which was reacted in the next step without further purification

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