반응 #8506
ord-dee3bbe8fbf245858780f3dd89a7ddd2
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
4-Hydroxymethylpyridine (20) (54.4 g, 0.50 mol) was dissolved in acetonitrile 202 ml. The solution was added dropwise to a mixture of thionyl chloride (65.3 g, 0.55 mol) and acetonitrile (109 ml) under 50° C. The mixture was stirred at the same temperature for 1 hour, then cooled to room temperature to yield a slurry (quantitative) of the objective (21).