반응 #84979

ord-c0926cee87cf4d5ba75590203872c79d

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타according to General Method 4B at 100° C

실험 절차

400 mg (purity 91%, 1.37 mmol) of 4-chloro-2-(5-chloro-2-oxo-1,2-dihydropyridin-4-yl)benzonitrile and 1.2 eq. of tert-butyl bromoacetate were reacted according to General Method 4B at 100° C. Yield: 421 mg (80% of theory)

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US09434690B2uspto-grants-2016_09