반응 #8448

ord-225d37cb45ef48c3874c2173b78719eb

반응 방정식

COCCN(C)c1ccc(OC)c(NC(N)=S)c1
{2-methoxy-5-[(2-methoxy-ethyl)-methyl-amino]-phenyl}-thiourea
Br.CC(=O)O
HBr AcOH
CS(C)=O
DMSO
→
COCCN(C)c1ccc(OC)c2nc(N)sc12
4-Methoxy-N7-(2-methoxy-ethyl)-N7-methyl-benzothiazole-2,7-diamine

반응물

COCCN(C)c1ccc(OC)c(NC(N)=S)c1
{2-methoxy-5-[(2-methoxy-ethyl)-methyl-amino]-phenyl}-thiourea
Br.CC(=O)O
HBr AcOH
CS(C)=O
DMSO

시약

없음

용매

CC(=O)O
AcOH

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

From {2-methoxy-5-[(2-methoxy-ethyl)-methyl-amino]-phenyl}-thiourea with HBr—AcOH (2 equiv.) and DMSO (1.1 equiv.) in AcOH. ES-MS m/e (%): 268 (M+H+, 100).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07087761B2uspto-grants-2006_08