반응 #84367

반응 방정식

4-(2-fluoro-4-nitrophenyl)morpholine

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title compound

수율 89.2%

3-fluoro-4-morpholinoaniline

수율 89.2%

용매

THF

반응 조건

후처리

1. 1
   여과The mixture was filtered through a celite pad
2. 2
   농축the filtrate was concentrated in vacuo

실험 절차

To a solution of 4-(2-fluoro-4-nitrophenyl)morpholine (15.0 g, 66 mmol) in THF (100 mL) was added Pd/C (3.0 g). The reaction mixture was stirred at rt under H2 for 12 h. The mixture was filtered through a celite pad, and the filtrate was concentrated in vacuo to give the title compound as a white solid (11.55 g, 89%).

출처