반응 #84065
ord-fdc47d94f1cb47239575a8bc12e2a82d
반응 방정식
2-chloroquinolin-6-ol
Intermediate 2
2-chloroquinolin-6-ol
4-borono-2-fluorobenzoic acid
→
2-fluoro-4-(6-hydroxyquinolin-2-yl)benzoic acid
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
Followed Scheme 3: Starting Materials: 2-chloroquinolin-6-ol (Intermediate 2) and 4-borono-2-fluorobenzoic acid. 1H NMR (CD3OD, 400 MHz): δ 8.54 (d, J=8.4 Hz, 1H), 8.20-8.06 (m, 3H), 8.06-7.96 (m, 2H), 7.55 (dd, J=9.2, 2.4 Hz, 1H), 7.32 (d, J=2.8 Hz, 1H). MS (ESI): m/z 283.6 [M+1]+.