반응 #83751

반응 방정식

methyl 1-methyl-indoline-2-carboxylate

lithium aluminum hydride

→

title compound

수율 100.3%

1-Methylindolin-2-ylmethanol

수율 100.3%

용매

tetrahydrofuran

반응 조건

후처리

1. 1
   기타A procedure similar to that described in Preparation 2

실험 절차

A procedure similar to that described in Preparation 2 was repeated, except that 8.0 g of methyl 1-methyl-indoline-2-carboxylate (prepared as described in Preparation 5), 1.91 g of lithium aluminum hydride and 250 ml of tetrahydrofuran were used, to give 6.85 g of the title compound having Rf=0.35 (on silica gel thin layer chromatography using a 2:1 by volume mixture of hexane and ethyl acetate as the developing solvent).

출처