반응 #83634

반응 방정식

2-Fluorobenzaldehyde

malonitrile

→

2-Fluorobenzylidenemalonitrile

용매

ethanol

반응 조건

후처리

1. 1
   온도The solution was heated
2. 2
   온도to reflux
3. 3
   기타Once the vigorous reaction
4. 4
   온도the solution was heated for 15 minutes
5. 5
   온도chilled
6. 6
   여과Crystals of product were filtered off
7. 7
   세척washed with ethanol, m.p. 122° C.

실험 절차

2-Fluorobenzaldehyde (15.8 ml) was dissolved in ethanol (100 ml) and to the stirred solution was added malonitrile (9.9 g). The solution was heated to reflux, the heating discontinued and piperidine (4 drops) was added. Once the vigorous reaction had diminished, the solution was heated for 15 minutes and then chilled. Crystals of product were filtered off and washed with ethanol, m.p. 122° C.

출처