반응 #83408

반응 방정식

meta-trifluoromethylphenol

sodium hydride

2-chloro-4-methylmercapto-6-(3-thienylmethyloxy)pyridine

→

4-methylmercapto-2-(3-thienylmethyloxy)-6-(meta-trifluoromethylphenoxy)pyridine

용매

dimethylformamide

반응 조건

후처리

1. 1
   workup.ADDITIONwas added

실험 절차

To a solution containing meta-trifluoromethylphenol (1.60 g, 0.0024×4.1 mol), sodium hydride (0.29 g, (ca.60% in mineral oil), 0.0024×3.0 mol) and CuI (0.22 g, 0.0024×0.5 mol) in dimethylformamide, 2-chloro-4-methylmercapto-6-(3-thienylmethyloxy)pyridine (0.64 g, 0. 0024 mol) was added and the resultant solution was refluxed for about 6 hours.

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