반응 #83175

반응 방정식

D-glucono1,5-lactone

tallowaminopropylamine

→

D-gluconamide

용매

methanol

반응 조건

후처리

1. 1
   기타A 1 liter round bottom flask equipped with a condenser, addition funnel
2. 2
   기타the heating mantle removed
3. 3
   온도The reaction mixture was cooled
4. 4
   여과The white product was filtered
5. 5
   세척washed with cold isopropanol (3×100ml)
6. 6
   기타dried under vacuum at 35° C.

실험 절차

A 1 liter round bottom flask equipped with a condenser, addition funnel, thermometer and mechanical stirrer was charged with D-glucono1,5-lactone (20.0 g, 0.11 mole) and methanol (56 g). The suspension was heated to 40° C. over 15 minutes and the heating mantle removed. Hydrogenated tallowaminopropylamine (36.0 g, 0.11 mole) was added dropwise over 15 minutes with rapid stirring. The reaction mixture was cooled and placed in a refrigerator at 0° C. overnight. The white product was filtered, washed with cold isopropanol (3×100ml) and dried under vacuum at 35° C. giving 46.2 g (83% yield) of hydrogenated tallowaminopropyl D-gluconamide with a melting point of 112°-115° C.

출처