반응 #83106

ord-457bc330f2854e96a29640d493b75a8b

반응 방정식

CC(C)(C)[Si](C)(C)OC[C@@H]1CCC(=O)O1
product
CC(C)(C)[Si](C)(C)OC[C@@H]1CCC(=O)O1
(S)-5-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]dihydro-2(3H)-furanone
COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1
Lawesson's Reagent
→
CC(C)(C)[Si](C)(C)OC[C@@H]1CCC(=S)O1
desired product
수율 114.0%
CC(C)(C)[Si](C)(C)OC[C@@H]1CCC(=S)O1
(S)-5-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]dihydro-2(3H)-furanthione
수율 114.0%

반응물

CC(C)(C)[Si](C)(C)OC[C@@H]1CCC(=O)O1
product
CC(C)(C)[Si](C)(C)OC[C@@H]1CCC(=O)O1
(S)-5-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]dihydro-2(3H)-furanone
COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1
Lawesson's Reagent

시약

없음

용매

Cc1ccccc1
toluene

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound is prepared by the procedure of Example 353 using 0.868 g of product from Example 359, 10 ml of toluene and 0.763 g of Lawesson's Reagent to give 0.530 g of the desired product.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05623081uspto-grants-1997_04