반응 #83064

ord-898193f0f65f4694bd51481f91ebc822

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    농축The reaction is concentrated in vacuo
  2. 2
    기타the residue purified by chromatography (silica gel: 0-10% diethyl ether/hexane)

실험 절차

A solution, under argon, of 0.183 g of product from Example 140 in 1.0 ml of dry methylene chloride is treated with 0.689 g of tetra-n-butyl-ammonium azide. The reaction mixture is stirred vigorously overnight at room temperature. The reaction is concentrated in vacuo and the residue purified by chromatography (silica gel: 0-10% diethyl ether/hexane) to give 0.061 g of the desired product.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05623081uspto-grants-1997_04