반응 #83063
ord-2bb411a2cc9c4bd1ba92e6db2f37a220
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반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타The reaction is quenched with 100 ml of saturated sodium sulfite
- 2추출extracted with methylene chloride
- 3기타the layers separated
- 4기타The organic layer is dried
- 5여과filtered
- 6농축concentrated in vacuo
- 7기타The residue is purified by
실험 절차
A 0° C. mixture, under argon, of 0.44 g of product from Example 139 in 5 ml of dry chloroform is treated with 0.55 ml of trimethylsilyl iodide. The reaction is stirred, in the dark, for 2 hours. The reaction is quenched with 100 ml of saturated sodium sulfite, extracted with methylene chloride and the layers separated. The organic layer is dried, filtered and concentrated in vacuo. The residue is purified by. chromatography (silica gel: 0-100% methylene chloride/hexane) to give 0.31 g of the product.