반응 #830422

ord-f5a6f365467b4f26a2b48a2a3246e0b3

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    농축The reaction mixture was then concentrated by evaporation under reduced pressure
  2. 2
    기타dried in vacuo

실험 절차

Following a procedure similar to that described in Example 1(c), 450 mg of 1-methyl-2-{2-[2-(4-phenylbutyl)phenoxy]ethyl}piperidine [prepared as described in step (a) above] dissolved in 5 ml of ethyl acetate were converted to the hydrdochloride by treating it with 0.4 ml of a 4N solution of hydrogen chloride in dioxane. The reaction mixture was then concentrated by evaporation under reduced pressure and dried in vacuo, to give 496 mg of the title compound as a colorless oil.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05556864uspto-grants-1996_09