반응 #830336

반응 방정식

2,5-dimethylaniline

benzotriazole

formaldehyde

→

N-(1-benzotriazolylmethyl)-2,5-dimethylaniline

수율 67.2%

용매

EtOH

반응 조건

후처리

1. 1
   workup.ADDITIONwas added gradually
2. 2
   기타the white solid which precipitated
3. 3
   기타was collected
4. 4
   세척washed with EtOH

실험 절차

A mixture of 2,5-dimethylaniline (27.4 g, 0.2 mol) and benzotriazole (23.8 g, 0.2 mol) in EtOH (300 mL) was stirred at 20° C. as 37% aqueous formaldehyde (16.1 g, 0.2 mol) was added gradually. After 30 minutes, the white solid which precipitated was collected and washed with EtOH to give N-(1-benzotriazolylmethyl)-2,5-dimethylaniline (33.9 g, 67% yield); mp (EtOH) 147°-149° C.

출처