반응 #82879

반응 방정식

hydrogen

hydrogen

1-Chloro-4-morpholino-2-naphthol

→

4-morpholino-2-naphthol

용매

potassium hydroxide

반응 조건

후처리

1. 1
   기타was absorbed (approximately 24h)
2. 2
   기타The palladium catalyst was removed by filtration

실험 절차

1-Chloro-4-morpholino-2-naphthol (15.0 g;0.057 mol), prepared as described in 2(a) above, was dissolved in 10% aqueous potassium hydroxide (100 ml) and was treated in the presence of palladium on charcoal (1.75 g;5%) at room temperature under 3 atmospheres of hydrogen until a stoichiometric amount of hydrogen was absorbed (approximately 24h). The palladium catalyst was removed by filtration and the filtrate neutralised with glacial acetic acid to afford 4-morpholino-2-naphthol as a white solid (8.5 g;65%), m.pt. 231°-232° C. ##STR19##

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