반응 #82447
ord-299d8a018f6644f7be2076f3bd417fef
반응 방정식
반응 조건
후처리
- 1추출is extracted once using diethyl ether
- 2기타is established in the aqueous phase at 0° C.
- 3추출The mixture is extracted
- 4세척the combined organic phases are washed several times with water and saturated sodium chloride solution
- 5기타after drying
- 6농축concentrating
실험 절차
2.5 g (0.1 mol) of lithium hydroxide are added at 0° C. to 10 g (0.07 mol) of ethyl trans-4-methyl-2,4-pentadienecarboxylate, dissolved in a solvent mixture of 75 ml of methanol, 17 ml of tetrahydrofuran and 2.5 ml of water, and the mixture is stirred for 20 hours at room temperature. After the mixture has been diluted with 200 ml of water, it is extracted once using diethyl ether, and a pH of 1 is established in the aqueous phase at 0° C. using concentrated hydrochloric acid. The mixture is extracted using diethyl ether, the combined organic phases are washed several times with water and saturated sodium chloride solution, and, after drying and concentrating, 6.1 g (76% of theory) of trans-4-methyl-2,4-pentadienecarboxylic acid are obtained. ##STR208##