반응 #82244

반응 방정식

2-formyl-5-methoxybenzoic acid

benzene n-hexane

diphenyldiazomethane

→

diphenylmethyl 2-formyl-5-methoxybenzoate

용매

chloroform

반응 조건

후처리

1. 1
   workup.ADDITION2030-2033, 1975) was added to the above solution until the reaction solution
2. 2
   기타The resulting reaction solution
3. 3
   기타was subjected to purification by silica gel column chromatography

실험 절차

4.87 g of 2-formyl-5-methoxybenzoic acid was dissolved in 30 ml of chloroform. With stirring at room temperature, a benzene/n-hexane (1:1) mixture solution of diphenyldiazomethane prepared in accordance with the procedure disclosed in Journal of the Chemical Society (Parkin I, pp. 2030-2033, 1975) was added to the above solution until the reaction solution showed a purplish red color. The resulting reaction solution was subjected to purification by silica gel column chromatography using a toluene/ethyl acetate mixture as an eluant to obtain 8.2 g of diphenylmethyl 2-formyl-5-methoxybenzoate as a viscous oil.

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