반응 #820889

반응 방정식

1-[7-(3-Chloro-phenylamino)-1,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-4-yl]-1-morpholin-4-yl-methanone

hydrochloric acid

→

title compound

수율 179.4%

1-[7-(3-Chloro-phenylamino)-1,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-4-yl]-1-morpholin-4-yl-methanone hydrochloride salt

수율 179.4%

용매

ethanol

반응 조건

후처리

1. 1
   기타The mixture was evaporated
2. 2
   기타triturated with diethyl ether
3. 3
   여과filtered off
4. 4
   기타then dried at 40° C. under vacuum

실험 절차

1-[7-(3-Chloro-phenylamino)-1,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-4-yl]-1-morpholin-4-yl-methanone (55 mg) was dissolved in warm ethanol (1 ml) and treated with a solution of 1M hydrochloric acid in diethyl ether (10 drops). The mixture was evaporated, triturated with diethyl ether and filtered off then dried at 40° C. under vacuum to afford the title compound (54 mg).

출처