반응 #81967

반응 방정식

4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid (2-pyridin-2-yl-ethyl)-amide

iodine

→

title compound

수율 91.3%

6-phenyl-2-(2-pyridin-2-yl-ethyl)-isothiazolo[5,4-d] pyrimidin-3-one

수율 91.3%

반응 조건

실험 절차

Using the procedure of Example 20, 14.0 g (41.6 mmol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid (2-pyridin-2-yl-ethyl)-amide were treated with 10.6 g (41.7 mmol) of iodine to give 12.7 g of the title compound after recrystallization from ethanol, mp 132°-133° C.

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