반응 #81889

반응 방정식

2-amino-4-(3,5-diacetylphenyl)amino-6-methylpyrimidine

methyl iodide

→

2-amino-4-(3,5-diacetylphenyl)amino-1,6-dimethylpyrimidinium iodide

용매

acetonitrile tetrahydrofuran

반응 조건

후처리

1. 1
   workup.ADDITION2, FIG. 1A: A suspension of Compound No
2. 2
   온도heated at 40°-45° C. under a reflux condenser for 18 hr
3. 3
   온도Cooling
4. 4
   여과filtration

실험 절차

Compound No. 2, FIG. 1A: A suspension of Compound No. 11 (2-amino-4-(3,5-diacetylphenyl)amino-6-methylpyrimidine) (0.284 g), was suspended in 1:1 acetonitrile-tetrahydrofuran was treated with methyl iodide (2 mL) and heated at 40°-45° C. under a reflux condenser for 18 hr. Cooling and filtration gave 0.35 g of 2-amino-4-(3,5-diacetylphenyl)amino-1,6-dimethylpyrimidinium iodide, mp 292° C.

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