반응 #81762

반응 방정식

2-(2,4,6-triiodophenoxy)-pentadecane

mesylate

3-nonanol

triiodophenol

potassium carbonate

2-(2,4,6-triiodophenoxy)-pentadecane

→

3-(2,4,6-Triiodophenoxy)-nonane

수율 67.3%

용매

—

hexanes

DMF

반응 조건

후처리

1. 1
   기타to provide a light brown oil

실험 절차

The mesylate of 3-nonanol (11.5 g, 51.9 mmol), triiodophenol (24.5 g, 51.9 mmol) and potassium carbonate (7.18 g, 51.9 mmol) were reacted in dry DMF (200 ml) as per 2-(2,4,6-triiodophenoxy)-pentadecane except at an oil bath temperature of 87° C. for 16 hrs. The reaction was processed as for 2-(2,4,6-triiodophenoxy)-pentadecane to provide a light brown oil. Flash column chromatography (silica, hexanes) provided 3-(2,4,6-Triiodophenoxy)-nonane (20.9 g, 67%) as a clear viscous oil.

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