반응 #816628

반응 방정식

2-Benzyloctahydropyrrolo[3,4-c]pyridine-5-carboxylic acid tert-butyl ester

hydrogen

→

title compound

수율 99.8%

octahydropyrrolo[3,4-c]pyridine-5-carboxylic acid tert-butyl ester

수율 99.8%

용매

methanol

반응 조건

후처리

1. 1
   여과The solution is filtered
2. 2
   농축concentrated

실험 절차

2-Benzyloctahydropyrrolo[3,4-c]pyridine-5-carboxylic acid tert-butyl ester (Example A26, 24.98 g, 78.8 mmol) in 400 mL of methanol is treated with 2.5 g of 20% Pd/C and shaken for 20.5 hours under 50 PSI of hydrogen. The solution is filtered and concentrated to afford 17.8 g of the title compound as a solid. MS APCI: m/z 228 (MH+).

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