반응 #8165

반응 방정식

m-tolylhydrazine hydrochloride

2-acetyl-3-oxo-butyric acid ethyl ester

pyridine

→

product

3,5-dimethyl-1-m-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester

용매

ethanol

반응 조건

후처리

1. 1
   기타The resulting oil was purified by flash chromatography

실험 절차

Similar to Example 1, equimolar amounts of m-tolylhydrazine hydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of a 50% pyridine in ethanol. The resulting oil was purified by flash chromatography to yield the named product as a solid (m.p. 46.5° C.–47.5° C.).

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