반응 #816394
ord-c6dd957d95a84db4b08e0aec670f0e11
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타for 15 hr
- 2기타After the completion of the reaction
- 3기타the acetone solvent was removed under reduced pressure
- 4추출the resultant was extracted with chloroform solution
- 5세척The extract was washed with saturated sodium bicarbonate solution
- 6세척was again washed with saline
실험 절차
One g of phytantriol (3.0 mmol, Sigma-Aldrich) was refluxed using deanstock apparatus for 15 hr in 25 ml of acetone solution with toluene sulfonic acid as catalyst. After the completion of the reaction, the acetone solvent was removed under reduced pressure and the resultant was extracted with chloroform solution. The extract was washed with saturated sodium bicarbonate solution and was again washed with saline to obtain 0.3 g of (2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-6,10,14-trimethyl-pentadecan-2-ol) of which 1- and 2-positions were protected.