반응 #816393
ord-4e8632ed821d4130ac3598ea3934cfda
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도by reflux for 5 hr in order
- 2추출The reaction mixture was extracted with 50 ml of methylene chloride solution
- 3세척washed with saline
- 4건조Following drying over anhydrous magnesium sulfate, filtration and concentration
실험 절차
The yielded phytandiol derivative (0.48 g) was dissolved in 25 ml of dimethyl formamide and 0.06 g (1.00 mmol) of sodium azide (Sigma-Aldrich) was added, followed by reflux for 5 hr in order to substitute azide for para-toluene sulfonyl group. The reaction mixture was extracted with 50 ml of methylene chloride solution and washed with saline. Following drying over anhydrous magnesium sulfate, filtration and concentration, 0.29 g of azido phytandiol derivative was yielded.