반응 #81639

반응 방정식

potassium cyanide

prussic acid

methyl methacrylate

→

methyl cyanoisobutyrate

methyl methacrylate

용매

N-methylpyrrolidone

반응 조건

후처리

1. 1
   기타A 500 milliliter (hereinafter abbreviated to "mL") flask equipped with a stirrer
2. 2
   workup.ADDITIONAfter the completion of the dropwise addition
3. 3
   온도the content was maintained at 120° C. for 2 hours
4. 4
   기타the reaction

실험 절차

A 500 milliliter (hereinafter abbreviated to "mL") flask equipped with a stirrer, a thermometer and two dropping funnels was charged with 203 g of N-methylpyrrolidone and 1.35 g of potassium cyanide, and to the content in the flask were added dropwise 40 g of prussic acid and 163 g of methyl methacrylate over a period of 4 hours, while the content was maintained at a temperature of 120° C. After the completion of the dropwise addition, the content was maintained at 120° C. for 2 hours to complete the reaction. As a result, methyl cyanoisobutyrate was formed at a conversion of methyl methacrylate (MMA) of 88.3% and at a selectivity of 98.1% based on the reacted MMA.

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