반응 #8160

반응 방정식

compound

3,5-dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester

hydrogen

→

1-(3-aminophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester

용매

ethanol

반응 조건

후처리

1. 1
   기타Upon completion of the reaction
2. 2
   여과the solution was filtered through Celite
3. 3
   농축the filtrate concentrated under vacuum
4. 4
   기타The named product slowly crystallized

실험 절차

The compound of Example 2 (1.8 g) was dissolved in ethanol then 0.2 g 5% Pd/C was added to the solution. The mixture was treated with hydrogen gas at 45 psi. Upon completion of the reaction, the solution was filtered through Celite, and the filtrate concentrated under vacuum. The named product slowly crystallized upon standing (m.p. 93° C.–95° C.).

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