반응 #8156

반응 방정식

p-tolylhydrazine

2-acetyl-3-oxo-butyric acid ethyl ester

pyridine

→

3,5-dimethyl-1-p-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester

용매

ethanol

반응 조건

후처리

1. 1
   기타The solvents were removed under vacuum
2. 2
   기타The named product was purified over silica gel (m.p. 47° C.–49° C.)

실험 절차

Similar to Example 1, p-tolylhydrazine (10 mmol, 1.8 g) and 2-acetyl-3-oxo-butyric acid ethyl ester (10 mmol, 1.7 g) were mixed in a solution of 50% pyridine in ethanol. The solvents were removed under vacuum. The named product was purified over silica gel (m.p. 47° C.–49° C.).

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