반응 #8152

반응 방정식

2-chloro-5-nitropyridine

hydrazine hydrate

→

(5-nitropyridin-2-yl)hydrazine

용매

ethanol

ethanol

반응 조건

후처리

1. 1
   workup.ADDITIONAt the end of the addition
2. 2
   기타The named product precipitated from the reaction medium
3. 3
   여과was collected by filtration
4. 4
   기타recrystallized from ethanol

실험 절차

To a solution of 2-chloro-5-nitropyridine (30 mmol, 5.0 g) in absolute ethanol was added a solution of hydrazine hydrate (320 mmol, 15.8 g) in ethanol using syringe pump. At the end of the addition, the reaction was refrigerated. The named product precipitated from the reaction medium, was collected by filtration, and recrystallized from ethanol.

출처