반응 #81389

반응 방정식

tetraethyl 2-[3-methoxy-4-hydroxy-1-naphthyl]ethane-1,1-diphosphonate

trimethylsilyl bromide

→

title compound

수율 67.0%

2-[3-Methoxy-4-hydroxy-1-naphthyl]ethane-1,1-diphosphonic Acid

수율 67.0%

반응 조건

후처리

1. 1
   기타hydrolysis

실험 절차

Following the same method as described in Example 2, 7.12 g (15 mmol) of the tetraethyl 2-[3-methoxy-4-hydroxy-1-naphthyl]ethane-1,1-diphosphonate obtained in Example 11 was treated with trimethylsilyl bromide, and then hydrolysis was effected to obtain 3.64 g of the title compound as pale yellow crystals. The yield was m.p.: 231°-232° C. (dec)

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