반응 #812356

반응 방정식

2-hydrazino-2-imidazoline hydrobromide

(1S,3aS,5S,7aR)-1-formyl-5-phenyl-7a-methylperhydroinden-3a-ol

→

title compound

수율 53.7%

(1S,3aS,5S,7aR)-1-[(E)-(2-Imidazolin-2-yl)hydrazono]methyl-5-phenyl-7a-methylperhydroinden-3a-ol hydrobromide

수율 53.7%

용매

water

dioxane

dioxane

반응 조건

후처리

1. 1
   기타The solution was evaporated to dryness under reduced pressure

실험 절차

To a solution of 0.93 g of 2-hydrazino-2-imidazoline hydrobromide in 45 ml of water and 30 ml of dioxane a solution of 0.89 g of (1S,3aS,5S,7aR)-1-formyl-5-phenyl-7a-methylperhydroinden-3a-ol in 30 ml of dioxane was added dropwise at room temperature and the mixture was stirred for 2 hrs. The solution was evaporated to dryness under reduced pressure and the residue was ground with ethanol/water then with ethanol to give 0.78 g of the title compound (I-al) as a white solid.

출처