반응 #81034

반응 방정식

2,6-di-tert-amylphenol

benzaldehyde

piperidine

→

title compound

수율 41.7%

2,6-Di-tert-amyl-4-benzylidene-cyclohexa-2,5-dienone

수율 41.7%

용매

heptane

반응 조건

후처리

1. 1
   기타The solution is then evaporated in vacuo
2. 2
   기타the residue chromatographed twice on silica gel with hexane

실험 절차

6.0 g (0.026 Mol) of 2,6-di-tert-amylphenol, 2.75 g (0.026 mol) of benzaldehyde and 4.37 g (0.05 1 mol) of piperidine are refluxed under nitrogen in 50 ml of heptane on a Dean-Stark trap for 24 hours. The solution is then evaporated in vacuo and the residue chromatographed twice on silica gel with hexane and then with hexane:ethyl acetate (9:1 ) to give 3.5 g of the title compound as a thick yellow oil.

출처