반응 #80895

ord-c08e66a8408a4e4eb012f3af00073397

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

In a similar manner, 2,4,6-triamino-5-chloroquinazoline can be reacted with 3,4,5-trimethoxybenzaldehyde and hydrogen in the presence of Raney nickel in 2-ethoxyethanol, affording the corresponding 2,4-diamino-6-[(3,4,5-trimethoxyphenylmethyl)imino]quinazoline. Step C of Example 15 describes in detail the preparation of this compound. In a similar manner there may also be prepared 2,4-diamino-6-(substituted-aminomethyl)quinazolines.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05616718uspto-grants-1997_04