반응 #80266

반응 방정식

N,N-bis[2-((phenoxycarbonyl)oxy)ethyl]-N-methylamine

acetonitrile

dimethylsulfate

→

4

N,N-Bis[2-((phenoxycarbonyl)oxy)ethyl]-N,N-dimethylammonium Methylsulfate

용매

ether

반응 조건

후처리

1. 1
   기타To a 1000 ml three-necked round-bottomed flask fitted with a reflux condenser, magnetic stirrer
2. 2
   workup.ADDITIONinternal thermometer, addition funnel, and argon inlet
3. 3
   workup.ADDITIONAfter addition
4. 4
   온도the mixture is heated
5. 5
   온도to reflux for 2 h
6. 6
   기타The product precipitates from the mixture after approximately 15 min

실험 절차

To a 1000 ml three-necked round-bottomed flask fitted with a reflux condenser, magnetic stirrer, internal thermometer, addition funnel, and argon inlet are added N,N-bis[2-((phenoxycarbonyl)oxy)ethyl]-N-methylamine (100.00 g, 0.278 mol), acetonitrile (270 ml), and dimethylsulfate (35.93 g, 0.278 mol) over 10 min. After addition is complete, the mixture is heated to reflux for 2 h. The cooled mixture is treated with ether (500 ml). The product precipitates from the mixture after approximately 15 min to give 4 as a white powder, 126.26 g (93%): mp 85°-87° C.

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