반응 #799650

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tert-butyl 2-benzylhexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate

→

title compound

수율 60.0%

tert-butyl hexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate

수율 60.0%

용매

EtOAc

반응 조건

후처리

1. 1
   여과filtered
2. 2
   농축The filtrate was concentrated in vacuo

실험 절차

To a solution of tert-butyl 2-benzylhexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate (1.60 g) in EtOAc was added a catalytic amount of 20% Pd(OH)2/C. The suspension was stirred for 3 h at room temperature under H2 and filtered. The filtrate was concentrated in vacuo to give the title compound as colorless oil (0.68 g, 60%). The crude product was used for the next step without further purification. The compound was characterized by the following spectroscopic data: MS (ESI, pos. ion) m/z: 227.4 (M+1).

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