반응 #794507
ord-6f9395cddc904cd1ba75f017e0cd558b
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상세 조건
See reaction.notes.procedure_details.
후처리
- 1세척washed with saturated sodium bicarbonate solution
- 2건조The organic layer was dried over sodium sulfate
실험 절차
A solution of benzyl (cis-3-hydroxycyclobutyl)carbamate (intermediate 47, 0.3 g, 1.356 mmol), p-toluenesulfonyl chloride (0.284 g, 1.492 mmol), and triethylamine (0.567 ml, 4.07 mmol) in dichloromethane (2.71 ml) was stirred at room temperature for 14 hours. The mixture was diluted with dichloromethane and washed with saturated sodium bicarbonate solution. The organic layer was dried over sodium sulfate, rotovapped, and advanced to next step directly.